This post should provide you with all the information: both physiologically and biochemically needed to understand the clotting cascade and its many steps.
The clotting cascade is one of the most difficult things for students of medical physiology to learn. There are many different steps that require many different inputs to facilitate the phenomenon of blood clotting.
Note the many different types of input that initiate this process.
One of the most commonly asked questions when working with students is: Why so many steps?
Aside from the Evolutionary process that merged individual cells to whole communities and then organs and organ systems, clotting cascade is a great example of inter system interactions that optimize a process, in this case via amplification.
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